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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGAM5
All Species:
25.45
Human Site:
T274
Identified Species:
46.67
UniProt:
Q96HS1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HS1
NP_612642.1
289
32004
T274
N
G
R
V
A
L
R
T
L
G
D
T
G
F
M
Chimpanzee
Pan troglodytes
XP_509498
465
51564
T274
N
G
R
V
A
L
R
T
L
G
D
T
G
F
I
Rhesus Macaque
Macaca mulatta
XP_001083353
235
26735
L221
G
R
V
A
L
R
T
L
G
D
T
G
F
M
P
Dog
Lupus familis
XP_543346
289
31978
T274
D
G
R
V
A
L
R
T
L
G
D
T
G
F
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX10
288
31976
T273
N
G
R
V
A
L
R
T
L
G
D
T
G
F
M
Rat
Rattus norvegicus
Q562B5
288
32042
T273
N
G
R
V
A
L
R
T
L
G
D
T
G
F
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510978
229
26244
L215
G
R
V
A
L
R
M
L
G
D
T
G
F
M
P
Chicken
Gallus gallus
XP_415083
212
24106
L198
G
R
V
A
L
R
T
L
G
D
T
G
F
M
P
Frog
Xenopus laevis
Q5FWM4
275
30968
M260
N
G
N
V
S
I
R
M
L
G
D
S
G
F
M
Zebra Danio
Brachydanio rerio
Q502L2
289
32155
A274
S
G
R
V
S
L
R
A
L
G
D
S
G
F
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46084
289
33147
Y265
S
G
N
V
S
I
K
Y
L
G
D
S
G
F
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09422
284
32472
S269
K
G
H
V
S
V
R
S
I
G
D
I
G
H
L
Sea Urchin
Strong. purpuratus
XP_793164
286
31924
A271
S
G
R
V
S
L
R
A
L
G
D
A
G
F
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
79.9
93
N.A.
93.4
92.7
N.A.
70.9
64.3
65
64.7
N.A.
46
N.A.
42.5
53.6
Protein Similarity:
100
62.1
81.3
97.5
N.A.
96.1
96.8
N.A.
76.8
70.5
78.1
77.1
N.A.
61.9
N.A.
59.1
67.1
P-Site Identity:
100
93.3
0
93.3
N.A.
100
100
N.A.
0
0
66.6
73.3
N.A.
53.3
N.A.
40
73.3
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
0
0
86.6
93.3
N.A.
86.6
N.A.
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
39
0
0
16
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
24
77
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
24
70
0
% F
% Gly:
24
77
0
0
0
0
0
0
24
77
0
24
77
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
16
0
0
8
0
0
8
0
0
8
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
24
54
0
24
70
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
0
24
62
% M
% Asn:
39
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
24
54
0
0
24
70
0
0
0
0
0
0
0
0
% R
% Ser:
24
0
0
0
39
0
0
8
0
0
0
24
0
0
0
% S
% Thr:
0
0
0
0
0
0
16
39
0
0
24
39
0
0
0
% T
% Val:
0
0
24
77
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _